Pisillo Italian Panini Introduce
In a city filled with countless dining options, it takes a truly special place to stand out. Pisillo Italian Panini, located at 110 W 38th St, has done just that by perfecting a single, simple concept: the Italian sandwich. But to call these creations "sandwiches" feels like an understatement. They are, as one customer famously put it, "a foot and a half long brick of a sandwich." This is a place that has earned its reputation not through flashy marketing, but through the sheer quality, authenticity, and staggering size of its paninis. A visit to Pisillo is a pilgrimage for anyone who loves genuine Italian ingredients piled high on fresh, high-quality bread. You can find people walking for miles, through rain or sun, just to get their hands on one of these stupendous sandwiches. The experience is almost an event in itself—the massive size and weight of the sandwich in its simple white bag makes it feel like you're carrying a culinary treasure back to your destination.
Pisillo Italian Panini is more than just a sandwich shop; it's an authentic Italian restaurant experience in a casual, fast-food setting. The owners, a dedicated husband and wife team, have brought the flavors of their home country to the Big Apple, using high-quality imported meats, cheeses, and spreads. The business is identified as women-owned, adding to its unique local character. The atmosphere is casual and friendly, with a welcoming vibe that makes it perfect for a quick bite or a solo dining adventure. The service is often praised for being incredibly fast and efficient, which is a major plus for the busy Midtown crowd. Despite the speed, there is no compromise on quality. Each panini is prepared with care, ensuring that every bite is packed with flavor. The menu, named after Italian cities, is extensive, offering a dizzying array of combinations to suit every palate, including a dedicated vegetarian option. It’s a place that captures the spirit of true Italian comfort food, providing a simple yet deeply satisfying meal that’s both a great value and an unforgettable experience.
Pisillo's reputation extends beyond its size. Customers rave about the amazing flavor and fresh ingredients. The bread, sourced from a long-standing Brooklyn bakery, is a key component, providing the perfect base for the generous fillings. Whether you’re a local grabbing lunch or a tourist looking for an authentic taste of New York, Pisillo delivers a dining experience that is both memorable and delicious. The fact that many customers find they can't finish an entire sandwich in one sitting only adds to the incredible value, making it a meal that can last all day. It's this combination of huge portions, high-quality ingredients, and genuine Italian passion that has made Pisillo Italian Panini a beloved fixture in Midtown.
---Pisillo Italian Panini is conveniently located at 110 W 38th St, New York, NY 10018. This prime location places it in the heart of Midtown, making it easily accessible from many of the city's most popular destinations. The restaurant is situated on a busy street, surrounded by corporate offices, making it a go-to spot for a lunchtime crowd. Its central address also means it is a great place for tourists looking for a quick and authentic Italian meal during a day of sightseeing.
The restaurant is easily reachable by public transportation. It is a short walk from major subway hubs, including the Times Square–42nd Street and Herald Square stations, which serve a vast number of lines (1, 2, 3, 7, A, C, E, B, D, F, M, N, Q, R, W, and S). This makes Pisillo accessible from nearly any neighborhood in New York City. For those with mobility needs, the establishment has a wheelchair accessible entrance, ensuring that all customers can comfortably enjoy the great food. Additionally, for those who drive, the area offers free street parking, a rare and welcome amenity in Midtown. The combination of its central location, easy transit access, and convenient amenities makes Pisillo Italian Panini a perfect destination for anyone in the city looking for a top-tier Italian sandwich experience.
---Dine-in: Pisillo offers a casual and cozy seating area where you can enjoy your gigantic panini fresh. It's a no-frills setting that focuses on the food, making it ideal for a quick, fulfilling lunch.
Takeout: Given the size of the sandwiches, takeout is a very popular option. You can grab your order and enjoy it on the go or back at your office, home, or hotel. The service is known to be very fast, perfect for a quick bite.
Delivery: For ultimate convenience, Pisillo Italian Panini offers both standard and no-contact delivery, allowing you to have their famous sandwiches brought right to your door. This is a great service for a busy day or when you'd prefer to stay in.
Curbside Pickup: A modern and efficient service, curbside pickup lets you order ahead and have your food ready for a quick and easy pickup without having to leave your car.
Authentic Italian Panini: Pisillo is known for its genuine Italian flavors. The paninis are made with high-quality, authentic ingredients, including imported meats, cheeses, and spreads, ensuring a true taste of Italy.
Gigantic Portions and Value: The sandwiches are famously huge. One panini is often enough for two people, or a hearty lunch and dinner for one. This makes them an incredible value for the cost, offering a satisfying meal that lasts.
Women-Owned Business: Pisillo Italian Panini is a proud women-owned business, adding a unique and admirable local character to the establishment.
Fresh and Fast Service: Despite the complex nature of the sandwiches, the service is remarkably fast and friendly. The staff is efficient and dedicated to getting your order right, even during the busiest lunch rushes.
Diverse Menu: The menu is extensive and features a wide variety of paninis named after Italian cities. This variety ensures there's a combination for every taste, from classic prosciutto and mozzarella to unique mixes with roasted peppers and truffle oil. Vegetarian options are also available.
Casual and Friendly Atmosphere: The vibe at Pisillo is simple, casual, and welcoming. It's a great spot for a quick and comfortable meal, whether you're alone or with a group. The atmosphere is also LGBTQ+ friendly and good for kids, making it an inclusive space.
For more information, to place a takeout order, or to inquire about delivery, you can contact Pisillo Italian Panini directly at their provided phone number. Their central Midtown location makes it a convenient and popular destination for a delicious and filling Italian meal. The friendly staff are always ready to assist and ensure you have a great experience.
Address: 110 W 38th St, New York, NY 10018
Phone: (212) 933-0775
---With an extensive menu featuring dozens of panini options, deciding what to order at Pisillo Italian Panini can be a delightful challenge. Many customers recommend the sandwiches named after Italian cities, and a few stand out as must-tries. A great place to start is with the signature Pisillo Panini, which is a glorious combination of Prosciutto di Parma, porchetta, buffalo mozzarella, roasted peppers, arugula, and balsamic dressing. This is a true feast and a great representation of what makes this place special. Another top choice is the Napoli, which features prosciutto di parma, buffalo mozzarella, arugula, and extra virgin olive oil, offering a classic and clean flavor profile.
For those who love a bit of a kick, the Palermo, with sopressata, fresh mozzarella, and hot peppers, is a fantastic option that delivers a spicy and savory punch. The Ariccia, with porchetta, provolone cheese, artichokes, arugula, and truffle oil, is also a customer favorite, showcasing a rich and earthy flavor. If you're looking for a vegetarian option, the Vegetarian Panini is a great choice, packed with flavorful ingredients like sun-dried tomatoes, roasted peppers, artichokes, and arugula. It's clear that no matter what you choose, you're getting a huge, high-quality sandwich. The key is to be prepared for the sheer size and know that you’re getting an incredible value for your money. With so many amazing options, the best thing to do is pick one that sounds appealing and dive into the delicious, authentic world of Pisillo's Italian paninis.
Pisillo Italian Panini Menu
Special
- Marinated Mushroom
Italian Panini
- Milano $16.90
- Napoli $16.90
- Roma $16.90
- Firenze $16.90
- Parma $16.90
- Bologna $15.90
- Genova $16.90
- Palermo $16.90
- Trento $16.90
- Torino $16.90
- Bari $15.90
- Perugia $15.90
- Aosta $15.90
- Trieste $15.90
- Catanzaro $15.90
- Verona $15.90
- Benevento $14.90
- Campobasso $12.90
- Ancona $12.90
- Vaticano $12.90
- San Marino $12.90
- Vegetarian $14.90
- Pisillo $17.90
- New York $16.90
- Sorrento
- Positano $16.90
- Ariccia $16.90
- Montesarchio $16.90
- Sant'agata $16.90
- Pompei $16.90
- Ischia $15.90
- Capri $14.90
Others
- Milano $16.90
- Napoli
- Roma
- Firenze $16.90
- Parma $16.90
- Bologna $15.90
- Genova $16.90
- Palermo $16.90
- Trento $16.90
- Torino
- Bari $15.90
- Venezia $16.90
- Cagliari $15.90
- L'aquila $16.90
- Aosta $15.90
- Perugia $15.90
- Trieste $15.90
- Catanzaro $15.90
- Verona $15.90
- Benevento $14.90
- Campobasso $12.90
- Ancona $12.90
- Vaticano $12.90
- San Marino $12.90
- Vegetarian $14.90
- Pisillo $17.90
- New York $16.90
- Sorrento $16.90
- Positano $16.90
- Ariccia $16.90
- Montesarchio $16.90
- Sant'agata $16.90
- Ischia $15.90
Pisillo Italian Panini Details
From the business
- Identifies as women-owned
Service options
- Curbside pickup
- No-contact delivery
- Delivery
- Takeout
- Dine-in
Popular for
- Lunch
- Solo dining
Accessibility
- Wheelchair accessible entrance
- Wheelchair accessible parking lot
Offerings
- Coffee
- Comfort food
- Quick bite
- Vegetarian options
Dining options
- Lunch
- Dinner
- Counter service
- Dessert
- Seating
- Table service
Amenities
- Wi-Fi
- Wi-Fi
- Restroom
Atmosphere
- Casual
Crowd
- Family-friendly
- LGBTQ+ friendly
Payments
- Credit cards
- Debit cards
- NFC mobile payments
- Credit cards
Children
- Good for kids
Parking
- Free street parking
Pets
- Dogs allowed outside
Pisillo Italian Panini Photos










Pisillo Italian Panini Location
Pisillo Italian Panini
110 W 38th St, New York, NY 10018, USA
Pisillo Italian Panini Reviews
ingredientscostitalian sandwichchoicesrollsbryant parksharelunchcheesessemolina bread
★ 5★ 4★ 3★ 2★ 1Ughhhhhh…. One of the most convenient Italian sandwich places in New York City. I walk 10 minutes through thick rain or burning sunlight to get here for my foot and half long brick of a sandwich because that’s how much food they put in these gigantic sandwiches. When I walk back to eat this thing I swear people think I have a broken arm or something because of the way I carry my sandwich looks like I’m in a sling and cast, the white bag covering the stupendous sized sandwich also goes to illustrate the picture for you.
June 10 · Hank PaulsonAmazing Panini. Great value for the cost. The sandwiches are huge and so tasty it's hard not to eat too much of it at one time. Service is also very friendly and fast.
July 17 · JoelPisillo might be the closest you’ll get to Italy without crossing the Atlantic. The staff chats in Italian, the deli vibes are charmingly loud and proud, and the sandwiches? Absolutely massive—roughly the size of your forearm, no exaggeration. The dried tomato, the semolina bread, the cheese—each ingredient lands with clarity and purpose, fresh and composed like a well-rehearsed aria. Highly recommended!
May 07 · Yunong ShiThis place is a gem. Clean, excellent service and huge portions! They slice the meat to order, house made dressing and amazing quality. I will be craving this. Definitely order #26, the Pisillo. Bonus, they have a fair amount of seating and good music.
March 11 · Eric AltmanI used to go to Subway for "healthy" food around here until I came across Pisillo: what an upgrade. The staff is super friendly and helpful. The bread is amazing, and the portion is humongous. The food in general is fresher than any chain restaurant I tried. I'm glad I gave this place a try and never regret it. A big shout out to the manager (I'm sorry I didn't catch her name).
January 17 · Jamil Amarti
More restaurants near me

370 7th Ave Suite 101, New York, NY 10001, USA

370 7th Ave, New York, NY 10001, USA

370 7th Ave Suite 103, New York, NY 10001, USA

220 W 31st St, New York, NY 10001, USA

304 W 34th St., New York, NY 10001, USA

370 7th Ave, New York, NY 10001, USA

370 7th Ave, New York, NY 10001, USA

4 Pennsylvania Plaza, New York, NY 10001, USA

316 W 34th St., New York, NY 10001, USA

355 7th Ave, New York, NY 10001, USA

383 W 31st St, New York, NY 10001, USA

316 W 34th St., New York, NY 10001, USA
Categories
Top Visited Sites






Trending Dining Insights Posts





